radiance Radiotherapy planning system for IORT

radiance, the intraoperative radiation therapy (IORT) planning system, improves IORT safety by providing a simulated display of the therapy result. This allows the specialist, outside the stress of the operating theater, to adjust the parameters in pursuit of the desired result.

MPR and Volume Rendering

The state-of-the-art 3D graphic engine provides high-quality Multiplanar Reconstruction (MPR) and a volumetric display of the patient’s image in real time. Users can rotate the view, pan left and right and zoom in and out instantly.

The isodose surfaces are overlaid on both the 2D and 3D images.

The contrast window and opacity table can be used to improve the image and show the anatomic features and regions of interest.

The patient can be placed in a supine or prone position.


radiance has a group of complete tools for precision measurement of the distances and angles in the scene.

Segmentation and DVH

The segmentation tool is used to pinpoint the areas of interest in the procedure, i.e., the regions to be treated, the regions to be protected and the regions that are resected during surgery.

These regions can be shown in outline or removed from the image to simulate the resected tumor. A Dose-Volume Histogram (DVH) is calculated for all identified risk regions, allowing users to optimize treatment parameters before going ahead with the treatment itself.


With radiance the IORT applicators are modelled and users can manipulate them to identify the entry points and make sure all the surfaces of the tumor bed are irradiated. Users can obtain an estimate of the depth and radiation to be received by the tissues for the desired diameter and the applicator angle or energy. The radiation oncologist can work out the best solution before or during the operation, cutting down the operation time and reducing stress.

Several studies can be loaded at once allowing the comparison of several different scenarios for a single case or of different cases. The pre-planning results can also be compared with the final results (the real result).

pencil beam dosimetry

radiance’s dosimetry calculation system is based on an adapted and validated version of the pencil beam algorithm used in external beam radiotherapy.

The calculation method opens up a new era in IORT dosimetry, showing a more precise view of how radiation interacts with tissue and making the result of the therapy much more accurate.

radiance allows pre-treatment simulation (design and testing) of bolus inserts and radiation protection devices, reducing the uncertainty of the whole procedure.


One of the main limitations on IORT development up to now has been the lack of any complete and uniform procedure-documentation method for comparing results and complications. When the IORT clinical program results are presented, the usual documentation factors are energy and applicator parameters (diameter and angle).

radiance stores all the treatment information generated with the system, including not only beam energy and applicator parameters but also position and orientation (in relation to the patient and the LINAC), the information on the regions and the patient’s image. The case can therefore be reproduced fairly easily.

This documentation can be stored before the treatment (during preplanning) and also after the actual procedure, recording all the final amendments of the original plan.

Working Group

Planning studies can be exported to other workstations. The remote display tool allows users to share their plans with other remote users in real time.

radiance is a communication tool for liaison between all IORT specialists: radiation oncologists, surgeons and physicists. Users can assess the plan with other colleagues (in the same workstation or another one) before putting it into practice, thus improving the safety of the whole procedure.

Clinical Trials

Clinical trials have shown that radiance users achieve a high level of faithful reproduction, improving their knowledge of the radiosurgery procedure in itself.

The IORT plan, sometimes defined before the treatment itself, allows simulation of different scenarios and interevaluation with other specialists (radiation oncologists, surgeons and physicists).